Glioma Pipeline constitutes 180+ key companies continuously working towards developing 200+ Glioma treatment therapies, analyzes DelveInsight.
Glioma Overview:
Gliomas are tumors that originate in the glial cells of the brain or spinal cord, which support the nervous system. They are the most common type of central nervous system (CNS) tumors and are known for their infiltrative nature. Gliomas are classified based on the type of glial cell involved—astrocytes, oligodendrocytes, or ependymal cells—and vary in severity from low-grade (slow-growing) to high-grade (aggressive and malignant).
Historically, classification relied on histopathological features like diffuse astrocytomas or oligodendrogliomas. However, modern approaches emphasize molecular and genetic markers for more accurate diagnosis, prognosis, and treatment planning. Gliomas are graded on a scale from I to IV, depending on cell proliferation and the presence of necrosis. The three main types include astrocytomas, oligodendrogliomas, and ependymomas, and are further grouped into low-grade (grades I–II) and high-grade (grades III–IV) based on their biological behavior and molecular features. Glioblastoma is the most aggressive form, while pilocytic astrocytoma is the least malignant.
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“Glioma Pipeline Insight 2025” report by DelveInsight provides a comprehensive analysis of the ongoing clinical development activities and growth prospects across the Glioma Therapeutics Market.
Key Takeaways from the Glioma Pipeline Report
DelveInsight’s Glioma pipeline report depicts a robust space with 180+ active players working to develop 200+ pipeline therapies for Glioma treatment.
In April 2025, Boston Scientific Corporation initiated the FRONTIER feasibility study to assess the safety of the TheRaSphere Glioblastoma (GBM) device in patients with recurrent GBM. Glioblastoma (GBM) is an extremely aggressive brain cancer with a poor prognosis.
Key Glioma companies such as CellabMED, Oblato, BioMed Valley Discoveries, PharmAbcine, Day One Biopharmaceuticals, I-Mab Biopharma, Chimerix, Medicenna Therapeutics, Daiichi Sankyo, Eli Lilly and Company, Candel Therapeutics, AstraZeneca, Aveta Biomics, Angiochem, Arog Pharmaceuticals, Boehringer Ingelheim, BioMimetix, Bexion Pharmaceuticals, CANbridge Life Sciences, Crimson Biopharma, Epitopoietic Research Corporation, Stemgen, and others are evaluating new drugs for Glioma to improve the treatment landscape.
Promising Glioma pipeline therapies in various stages of development include ONC 201, Enzastaurin, MDNA55, Safusidenib, CAN-3110, MB-101, and others.
Glioma Pipeline Analysis
The report provides insights into:
The report provides detailed insights into the key companies that are developing therapies in the Glioma Market.
The report also evaluates different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Glioma treatment.
It analyzes the key companies involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
It navigates the emerging drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement, and financing details for future advancement of the Glioma market.
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Glioma Emerging Drugs
ONC 201: Chimerix
Enzastaurin: Denovo BioPharma
MDNA55: Medicenna Therapeutics, Inc.
Safusidenib: AnHeart Therapeutics
CAN-3110: Candel Therapeutics
MB-101: Mustang Bio
Glioma Companies
More than 180 leading companies are actively working on developing treatments for Glioma. Among them, Biohaven Pharmaceuticals, Inc. has the most advanced drug candidates, currently in Phase III clinical trials.
DelveInsight’s report covers around 200+ products under different phases of clinical development like
Late stage products (Phase III)
Mid-stage products (Phase II)
Early-stage product (Phase I) along with the details of
Pre-clinical and Discovery stage candidates
Discontinued & Inactive candidates
Glioma pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
Intravenous
Subcutaneous
Oral
Intramuscular
Glioma Products have been categorized under various Molecule types such as
Monoclonal antibody
Small molecule
Peptide
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Glioma Pipeline Therapeutic Assessment
• Glioma Assessment by Product Type
• Glioma By Stage
• Glioma Assessment by Route of Administration
• Glioma Assessment by Molecule Type
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Table of Content
1. Report Introduction
2. Executive Summary
3. Glioma Current Treatment Patterns
4. Glioma – DelveInsight’s Analytical Perspective
5. Therapeutic Assessment
6. Glioma Late-Stage Products (Phase-III)
7. Glioma Mid-Stage Products (Phase-II)
8. Early Stage Products (Phase-I)
9. Pre-clinical Products and Discovery Stage Products
10. Inactive Products
11. Dormant Products
12. Glioma Discontinued Products
13. Glioma Product Profiles
14. Glioma Key Companies
15. Glioma Key Products
16. Dormant and Discontinued Products
17. Glioma Unmet Needs
18. Glioma Future Perspectives
19. Glioma Analyst Review
20. Appendix
21. Report Methodology
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