DelveInsight’s “Atopic Dermatitis Treatment Market Insights, Epidemiology, and Market Forecast – 2034” report delivers an in-depth understanding of all Atopic Dermatitis types, historical and forecasted epidemiology as well as the Atopic Dermatitis market trends in the United States, EU4 (Germany, Spain, Italy, and France) and the United Kingdom, and Japan.
Discover which therapies are expected to grab the Atopic Dermatitis Market Share @ Atopic Dermatitis Market Outlook
Key Takeaways from the Atopic Dermatitis Market Report
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Atopic Dermatitis Epidemiology Segmentation in the 7MM
Download the report to understand which factors are driving Atopic Dermatitis Epidemiology trends @ Atopic Dermatitis Prevalence
Atopic Dermatitis Marketed Therapies
Upadacitinib (ABT-494) – discovered and developed by AbbVie scientists and marketed as RINVOQ – is a selective and reversible JAK inhibitor. JAKs are intracellular enzymes that transmit signals arising from cytokine or growth factor-receptor interactions on the cellular membrane to influence cellular processes of hematopoiesis and immune cell function. Within the signaling pathway, JAKs phosphorylate and activate signal transducers and activators of transcription (STATs), which modulate intracellular activity, including gene expression. Upadacitinib modulates the signaling pathway at the point of JAKs, preventing the phosphorylation and activation of STATs.
DUPIXENT (dupilumab) is an interleukin-4 (IL-4) receptor alpha antagonist. It is a human monoclonal antibody of the immunoglobulin G4 subclass that inhibits IL-4 and interleukin-13 (IL-13) signaling by specifically binding to the IL-4 receptor alpha subunit, which the IL-4 and IL-13 receptor complexes share. Dupilumab inhibits IL-4 signaling via the type 1 receptor and both IL-4 and IL-13 signaling via the type 2 receptor.
Atopic Dermatitis Emerging Therapies
Rocatinlimab (KHK4083/AMG 451) is an anti-OX40 human monoclonal antibody that inhibits and reduces the number of OX40-expressing pathogenic T cells responsible for driving systemic and local inflammatory responses. It has been reported that effector T cells expressing OX40 are present in the lesions of patients with atopic dermatitis and are critical in the disease pathophysiology. The initial antibody was discovered in collaboration between Kyowa Kirin US Research and La Jolla Institute for Immunology.
Tapinarof is a novel aryl hydrocarbon receptor agonist in development as a once-daily, steroid-free, and cosmetically elegant topical cream. Dermavant is developing it for the treatment of psoriasis and atopic dermatitis. Over 1,400 subjects have participated in 12 clinical trials for tapinarof. In the US, VTAMA cream is approved for the topical treatment of plaque psoriasis in adults.
To learn more about Atopic Dermatitis Treatment guidelines, visit @ Atopic Dermatitis Clinical Trials Assessment
Atopic Dermatitis Companies
Sanofi/Regeneron Pharmaceuticals, RAPT Therapeutics, Pfizer, Japan Tobacco, and Torii Pharmaceutical, Eli Lilly and Company, AbbVie, LEO Pharma, Incyte Corporation, Arena Pharmaceuticals, Oneness Biotech, Galderma, DS Biopharma, Janssen, AOBiome Therapeutics, Kymab, Qurient, Arcutis Biotherapeutics, Cara Therapeutics, Vanda Pharmaceuticals, and others.
Atopic Dermatitis Market Outlook
Several effective Atopic Dermatitis treatments have become available in recent years for adult and adolescent patients with Atopic Dermatitis, and more are in development. The current Atopic Dermatitis market uses several off-label therapies apart from pharmacological systemic treatment. Localized atopic itch is frequently treated with topical or intralesional therapeutic agents. Topical corticosteroids have been used for atopic dermatitis for decades. Pimecrolimus and tacrolimus, topical calcineurin inhibitors, are used as steroid-sparing agents for patients with atopic dermatitis. Phosphodiesterase-4 (PDE-4) inhibitors are an alternative option for the topical treatment of pruritis in atopic dermatitis. Oral antihistamines are commonly used for atopic itch. Additionally, phototherapy is efficacious in targeting atopic itch.
Atopic Dermatitis Treatment Market Landscape
Atopic dermatitis, also called eczema, is a chronic condition and the most common type of skin inflammation that usually starts in early childhood but can occur at any age and can be recurrent or persistent throughout life. In ‘dermatitis,’ ‘derm’ means ‘skin,’ and ‘itis’ means ‘inflammation.’ Thus, dermatitis is a skin inflammation characterized by itchiness, redness, and a rash caused by genetics, an overactive immune system, infections, allergies, and irritating substances. Half of the patients with moderate-to-severe eczema also have asthma, hay fever (allergic rhinitis), and food allergies; it is the most common chronic skin disease in children.
Learn more about the FDA-approved drugs for Atopic Dermatitis @ Drugs for Atopic Dermatitis Treatment
Scope of the Atopic Dermatitis Market Report
Table of Contents
1. Key Insights
2. Atopic Dermatitis Market Report Introduction
3. Atopic Dermatitis Market Overview at a Glance
4. Atopic Dermatitis Epidemiology and Market Methodology
5. Atopic Dermatitis Executive Summary
6. Atopic Dermatitis Market Disease Background and Overview
7. Atopic Dermatitis Epidemiology and Patient Population
8. Patient Journey
9. Key Endpoints in atopic dermatitis Clinical Trials
10. Marketed Therapies
12. Atopic Dermatitis: The 7MM Analysis
13. Atopic Dermatitis Market Access and Reimbursement
14. Atopic Dermatitis KOL Views
15. Atopic Dermatitis SWOT Analysis
16. Atopic Dermatitis Unmet Needs
17. Appendix
18. DelveInsight Capabilities
19. Disclaimer
About Us
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